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The cytotoxic and antibacterial activities of Sanguisorbae officinalis L., which is blown as a major tannin source, were investigated to check the possible use of natural nutraceutics or cosmetics. The S. officinalis inhibited cancer cell growth in a dose-dependant manner. Also, the clear zone against various bacteria such as Staphylococcus aureus, S. epidermidis, E. coli were evident at 0.5 and 1 ㎎/dusc. When the concentrations were 500 and 1,000 ppm. growth of all aerobic bacteria increased at early stage but decrease afterward. The results indicated that S. officinalis had the anti-skin cancer activity as well as antibacterial activity against skin-related bacteria.
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